HELP HIM.
HELP HIM.
HELP HIM.
Fuck all animal testing and every scientist participating in it.
Yeah. Fuck those scientists. Especially the ones that have created life saving things like penicilling, insuling. And its so shitty they used lab rats to test useless things like covid vaccines lately. I mean why to use poor rats. They could just have tested the vaccines with poor people.
And fuck cancer treatment too. Lets just treat people blindly, they are going to die anyway, why not make their last moments suffering just because you like mouses. Maybe we just should stop trying to cure cancer.
Computational biochemistry is slowly getting there. Alphafold was a big breakthrough, and there is plenty of ongoing research simulating more and more.
We can probably never get rid of animal testing entirely for clinical research, we’ll always need to validate simulations in animals before moving on to humans.
I do however agree that animal testing outside of clinical research approved by a competent independent ethics committee can fuck right off. (Looking at you, cosmetics industry)
We can probably never get rid of animal testing entirely for clinical research, we’ll always need to validate simulations in animals before moving on to humans.
Getting rid of animal testing is the exact purpose of organ-on-a-chip research! This is actual bioengineered cultures, not simulations (not dissing on computational biochemistry - also extremely important)
If you can test without the full animal, then models (in this context, models = what you use for testing, be it cultures or animals) based on human induced pluropotent stem cells (ie cells taken from live, adult humans and forced to revert to a stem cell status) in an in vitro setting can actually be more relevant to human physiology than live animal models.
There are a lot of caveats (if it were easy, it would already be done), and there are barriers needed to be overcome for in vitro models to even come close to in vivo and ex vivo models. But a lot of people are investing in it, not (only) due to ethics but also due to lower model cost and better match of in vitro results with the actual effect on a live human body.
I can give papers when I get home, if you want.
Edit: I went on a deep dive on medical applications: suffice it to say, this is useless for behavioral experiments
What's wrong with thalidomide? We can just put the shelves lower!
For those who don’t know, this is how some labs use rats and mice when the are uncooperative. I don’t think the intent is to hurt the mouse, just to contain it briefly.
Not saying it’s okay or not okay. Just saying why it’s like this.
it definitely doesn't hurt the mouse, maybe they're a bit uncomfortable but it's just all-round the best solution for everyone involved
This isn’t baking class 🥺
It can be, you just need to squeeze harder.
Worst icing ever
rats, rats, we are the rats
Noooooo. Poor rattie :(
They generally don't mind this
I'd like to see their survey results
This pic looks like the same from a post people talked about how this is used to transport lab rats around a lab, that it cam be comforting to them, comfy confinment or something. tldr the rat is safe (for a likely lab rat) and this is humane treatment.
Not really. It causes them stress. “Safe” and “Humane” are variable. But it definitely isn’t the “best” restraint method.
lifting and holding by the tail, and handling using a soft plastic restraint cone, resulted in significant increases in mean arterial pressure and heart rate compared with baseline.3 The authors concluded that being lifted in a restraint cone appeared to be the most disturbing handling method for the rats, followed by the tail method, as determined by prolonged duration of increased cardiovascular parameters as compared with the encircling or scruffing methods.3
As for example explored by this paper: https://pmc.ncbi.nlm.nih.gov/articles/PMC10844733/
The rat is safe in that it can't hurt itself or others, but they feel the same about this kind of confinement as humans do. I guess whether that counts as humane is a matter of opinion.
Unfortunately this is rather tame compared to the fucked up shit we put cute little ratties through in the name of science.
I know… :(.
I’m sure some of it is worthwhile. But knowing a couple applied researchers who work in animal labs, according to them a large amount of what is done is absolutely useless and only serves to get out a new useless product TM or publish a paper that looks good.
Ahh that's why my cake icing taste like Black Death
Ow lawd, he pipin
Despite all my rage
Despite all my nag*
Can images of animal abuse please be labeled as such and get a NSFW blur please?
Shame whoever took this
pocong rat
Its probably not a good way to transport them because that looks very stressful but it probably keeps them warm so it might be better than a metal cage.
It’s a decapi-cone… for euthanasia (sorry)
Can also be used for blood collection tho
Does anyone remember bonsai-kitty?
Apply directly to the cake
I'm not going to yuck Remmy's yum.
Does this hurt the rat?
The action of putting them in the tube doesn't. However, this is a rat used for testing of some kind so it will be hurt at some point
Maybe it’s in the control group
Eventually yes
Patisserat