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2 yr. ago

  • Ah, not to worry, even professionally it's very common to buy your wafers. I am on mobile data right now so I'll check out those videos later!

    Basically, every single machine that needs a vacuum chamber - so almost all non-wet processes, like physical/chemical vapor deposition, reactive ion etching, scanning electron microscopy (although a good optical microscope will do if you're not at the nano scale... Which is almost certainly the case if you're doing things at home).

    Honestly maybe I'm just too used to the lab setting and am underestimating how much you can actually do without vacuum processing. I'll take a look later: this all looked so out of the reach of an ordinary person that I never even considered following content creators who do this. Thank you!

  • Wait, I work in cleanrooms professionally. Fabricating my own semiconductors at home always seemed like a cool idea, but really out of reach. I kind of always wanted to keep old machines from the labs I worked at, but with such expensive things they never threw anything away (of course)!

    Isn't it prohibitively expensive and/or noisy? What type of projects do you do?

  • You're a very good person!

    My mother's dog was a dog we gave "temporary" shelter to... Five years ago. She's 10 now and we couldn't be happier. She came to us from a very difficult home situation (her previous owner had just escaped from a violent marriage, and we think the dog might have been a victim too, but nobody was ever able to prove anything). She's still a little monster and she's still very afraid of everything, but there's no comparing how she was when we adopted her and how she is now.

    I had an ex who lived somewhere where people often went to to abandon their dogs once they grew too old, too big or too aggressive. Her family also took in as many as they could: when we broke up, they had something along the lines of 10 dogs. It was very rewarding, too, as she got a good friend in each and every one of them. But it really hurts my heart to imagine that someone could be so cruel as to just abandon a dog like that, even hurt them.

  • It's true that barely anyone is into actually contributing, but I assure you a fair amount of people are into the actual open source implementations and are thankful for your efforts!

    Any game in particular you contributed to that you want to share?

  • We can probably never get rid of animal testing entirely for clinical research, we’ll always need to validate simulations in animals before moving on to humans.

    Getting rid of animal testing is the exact purpose of organ-on-a-chip research! This is actual bioengineered cultures, not simulations (not dissing on computational biochemistry - also extremely important)

    If you can test without the full animal, then models (in this context, models = what you use for testing, be it cultures or animals) based on human induced pluropotent stem cells (ie cells taken from live, adult humans and forced to revert to a stem cell status) in an in vitro setting can actually be more relevant to human physiology than live animal models.

    There are a lot of caveats (if it were easy, it would already be done), and there are barriers needed to be overcome for in vitro models to even come close to in vivo and ex vivo models. But a lot of people are investing in it, not (only) due to ethics but also due to lower model cost and better match of in vitro results with the actual effect on a live human body.

    I can give papers when I get home, if you want.

    Edit: I went on a deep dive on medical applications: suffice it to say, this is useless for behavioral experiments

  • My input: I've never searched for papers in Scihub directly. I usually find them off Google scholar or something, and then put the paywalled URL or the DOI (an identifier you can usually find in the paywalled website) in Scihub to go to that paper. I don't think search capabilities are in scihub's scope.