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Didn't they use large doses of nicotine?
I think it was more like a large amount of whiskey, a cloth to bite on and 3 to 5 people to hold you down whilst they sawed off your leg as quickly as possible.
If you were lucky, you'd get laudanum, which is a mixture of opium and alcohol.
That sounds absolutely awesome tbh
Opium. That and a solid strip of leather to bite down on.
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