The only drug that treats syphilis during pregnancy is in short supply. Untreated, the disease can pass to newborns, killing them or leaving them with disabilities. As cases rise sharply, the government isn’t doing much to prevent shortages.
The only drug that treats syphilis during pregnancy is in short supply. Untreated, the disease can pass to newborns, killing them or leaving them with disabilities. As cases rise sharply, the government isn’t doing much to prevent shortages.
Karmin Strohfus, the lead nurse at a South Dakota jail, punched numbers into a phone like lives depended on it. She had in her care a pregnant woman with syphilis, a highly contagious, potentially fatal infection that can pass into the womb. A treatment could cure the woman and protect her fetus, but she couldn’t find it in stock at any pharmacy she called — not in Hughes County, not even anywhere within an hour’s drive.
Most people held at the jail where Strohfus works are released within a few days. “What happens if she gets out before I’m able to treat her?” she worried. Exasperated, Strohfus reached out to the state health department, which came through with one dose. The treatment required three. Officials told Strohfus to contact the federal Centers for Disease Control and Prevention for help, she said. The risks of harm to a developing baby from syphilis are so high that experts urge not to delay treatment, even by a day.
Nearly three weeks passed from when Strohfus started calling pharmacies to when she had the full treatment in hand, she said, and it barely arrived in time. The woman was released just days after she got her last shot.
Last June, Pfizer, the lone U.S. manufacturer of the injections, notified the Food and Drug Administration of an “impending stock out” that it anticipated would last a year. The company blamed “an increase in syphilis infection rates as well as competitive shortages.”
You can dump on Pfizer if you want, but they don't seem to hold a patent and other manufacturers around the world have also dropped interest in this hard to make drug with limited (though growing steadily for a decade) demand. It is a collective decision, ie government, to commit to stockpiling certain drugs on a schedule so resources can be used efficiently in a round robin way and manufacturers are not expected to keep producing small quantities of a thousand different drugs all the time. I mean they should get bad press, but there might be more effective ways of ensuring the supply.
On the other hand, I am very happy to hear of a jail medical provider who cares so much about her patients.
Healthcare should not be left in the hands of private corporations. I don't want babies to die or be disabled because Pfizer decided a particular medicine wasn't profitable enough to warrant investment. Food, homes, medicine, and utilities are foundational for good quality of life. They should be guaranteed by the government, not left to an uncontrolled market to provide if it's good for their bottom line.
This is shocking because syphilis is treated with penicillin. I'm not an expert, but I've read that doxycycline can be used in non-pregnant patients. The injectable form of penicillin is required for pregnant patients like the woman in the story. And that's the one that's in short supply.