Elias Toufexis, who played protagonist Adam Jensen in Eidos Montreal’s Deus Ex: Human Revolution and Deus Ex: Mankind Divided, has said he has yet to be asked to reprise his role.
The characters will be voiced by an AI. Players will be astounded at the wide range of in-game dialog, and occasionally bemused when game characters insist that "the arsonist has oddly-shaped feet" and "The Human Torch is denied a bank loan."
Disappointing, but not surprising. I was hopeful when Square sold off their properties to Embracer, who at least seemed like they wanted to do something with Deus Ex, but with their recent financial troubles, it wouldn't be surprising if they scaled back any plans they had for the franchise.