I've had no issues using Lutris. When I add a game, I go through the Lutris menu and choose the Windows installer exe option (not at my computer, I can't remember the exact name.) I know I've done Fitgirl repacks, I think I've done a Dodi one.
Looking at SteamDB, it looks like it checks VC2015 is installed. So you'll want to check if your bottle has at least one of: vcrun2015, vcrun2017, vcrun2019 or vcrun2022. It's pretty likely that's a required dependancy.
It also installs "DirectX Jun 2010 Redist" which installs or updates a bunch of libraries, I think most if not all of these can be installed to your bottle too. I don't know which are required but it's a place to start.
There’s a lot of good advice in here. If shit hits the fan and nothing else works, you can install the repack in a Windows VM, copy the install directory to the host, and add the exe to Bottles. Easy money
Sometimes I find Dodi working and fitgirl not working, sometimes neither works, sometimes both work. I usually get issues related to unarc.dll and similar. I haven't done repacks (or much gaming for that matter) for weeks now, so I don't know.