Like the video game. It was actually a pretty good introduction to the lore, (which I only know surface level from playing the games and not digging real deep. So there may have been mistakes) and it was just about to get good, but, there just wasn't enough interest to sink more money in the franchise.
Jumper. It was setting up an interesting world with more depth than the first movie could delve. I loved that one of the characters was so cool that the author of the original novel went out and wrote another book just about the movie's character and it rocked.
Beetlejuice. It was such a popular movie that spawned a musical, a cartoon, various video games, etc yet there's only been the one movie. There's been talks about a sequel over the years but nothing has materialized yet.
A sequel to Prometheus that actually focused on getting answers from the engineers. Covenant had an interesting performance from Fassbender but nothing else.
The Road to El Dorado was the pilot for an animated series that never got greenlit. Massive missed opportunity, I would love to see "the continuing adventures of three latin rogues and a horse"
Although there were a lot of problems with Ender's Game, I was a little surprised that they didn't adapt any of the sequels. I mean I wouldn't have watched them, but it seemed like they went pretty all in on that first one to not at least try the second with a significantly reduced budget.
I'm gonna answer a slightly different question, What film am I surprised didn't get a sequel sooner? The Incredibles. Sure, it was a self-contained story, but it could've gone anywhere after that. The last scene with the undertaker was just teasing another Incredibles adventure. But instead we just kept getting toy stories.
By the time they did announce a sequel, it had been so long that I wasn't confident that it could live up to the original - and I was pretty much right, it wasn't a bad movie but I've never felt the desire to watch it again like I have the first a few dozen times. So yeah, that's one movie where I'm like "why didn't they ever make a sequ- ... oh, that's right they did"
I can't see anyone mentioning Titan A.E. man I love that movie, the mix of hand drawn animation and CGI was great for the time and I really enjoyed the world building.
Ninja Assassin. Okay, not a great film but it made a profit in the box office, the fight scenes were pretty sick, and it hinted at a little bit of world building with the mention of other clans.