Krita. I had a uni licence for Photoshop for years, even took a Photoshop course but still kept using Krita. It has an intuitive UI and all the tools I'll ever need.
RStudio+R is way better than any of its proprietary alternatives.
Blender. I'm no 3D modling expert but it does everything I as a hobbyist want to do with it and so much more. Nowadays, the UI is pretty decent, too.
Finally, the Lagrange browser is really good. The gemini protocol is kinda niche though, but if you're interested it's unreasonably pretty, well optimized and has a great UX. The guy who maintains it really puts his heart and soul into it.
The fact that you put those examples together with this Lagrange browser made me curious enough to check it, I had never heard of Gemini protocol before. So, simply put, thank you for sharing about this, I'm going to be installing Lagrange and start checking out geminispace.