I'm a cane user myself, but based on what my guide dog using friends have been through, it seems like you can just give up on getting picked up by Ubers. There is a dispute process, but that doesn't do you much good when you're stranded somewhere and two Uber drivers just drove off.
@pax I am also a cane user, but I often ask people about their guide dog experiences. Overall, they say walking is more fluid. A cane is meant to find obstacles, while a dog is meant to avoid them. I personally like my cane finding obstacles since they can also serve as landmarks or clues, but when walking a familiar route, I sometimes wish I could breeze right past them like a dog handler can.
As a cane user, there is a lot I can't imagine doing with only a guide dog. But I know that's only because I haven't experienced it myself. I'm sure there's a way to navigate unfamiliar areas, even if I don't understand it.