I hate to be nitpicky about a meme but I love to be nitpicky. This claims is based on bullshit statistics that the author made up or bent to his will. The Ottoman empire alone shows this to be incorrect but Rome too stands out. Besides, what would an arbitrary amount of time have to do with the collapse of complex economic systems. Its bullshit idealism and I hate seeing it.
Also worth pointing out that, while America may be 249 years old, no one would consider it an empire for the majority of that time. Its debatable, but I would argue we didn't really reach an empirical level of power until the late 40s, when we started taking over what was left of the British Empire's influence over the middle-eas5.
The US has always been a settler-colony, but it became more Imperialist after World War I with the inter-ally debts. It became world hegemon after the dissolution of the Soviet Union, however.
Average. It's just an average. I haven't verified whether the number is accurate (and often it's probably debatable what qualifies as an empire and at what point it fell) but some empires lasting way longer does nothing to disprove 250 years being the average lifespan.
The second part of what you said is still entirely correct of course, that number has no real predictive capabilities for the collapse of the USA.
It isn't though, I have seen the original source of this claim and its bs. The author just picks and chooses when empires begin and end so that it fits their claim. I would concede the point if it were ever actually an average.
When someone says "death to America", they aren't saying "death to Americans". A government/state is a regime, not all it's people, despite how much as nationalists love to stoke that sort of patriotism. So I have no problem with the slogan, I call for the fall of the US imperialist regime.
Despite all the and suffering it has caused and will cause, Trump admin has at least handed us the beginning of a breakdown in US hegemony as trust has eroded with other nations who are all busy pivoting away from it right now.
Unfortunately upon breaking the gridlock, other nations are scrambling to maintain the status quo rather than leaning into the future by redoubling commitments to address human and climate crises before it’s too late for the humans.