It's a near certainty, if you want your brain implant to be able to communicate with any device outside your skull. If it has Bluetooth or NFC then that's a vulnerability vector.
Witches do all sorts of things for curses, that doesn't necessarily mean that the conditions don't exist outside of witch curses. I don't think many people would disagree that being trans sucks, though, they just disagree about what it actually is and what to do about it.
The witch turned the creep into a woman and the spell was complete by the time she flew away. Unfortunately, like many women, the creep was born with the body of a man (she’s AMAB). Maybe the witch could have changed her body, too, but that would have made things far too easy, given that the point of the curse was to teach her empathy.
One witch made one man trans. It doesn't mean that the mission of all witches is to give out gender dysphoria, nor does it mean that trans people are trans because a witch did it. Life assigns these sorts of things apparently at random anyway.
I mean, a true sceptic could imagine that the witch in this comic had no magical power at all, but her words filtered down through the man's psyche to where he has always been struggling with his identity, and they gave him the excuse to face it.
I think it pokes against a popular idea of transforming into opposing sex. So many men imply that they would be transformed into a hot attractive woman. Not an unattractive one.
My first thoughts went to a hyper-fixation on weight and presentation/musculature/grooming. All the negatives of being/wanting-to-be a woman today, with none of the perks, and potentially no resolution.
You're downvoted, but as far as the behavior of the cursee is concerned, nope. She's still the same jerk she was before, just with a different gender. It isn't said whether or not her sexuality was changed as well.