Would you rather only able to see one thing, hear one thing, feel one thing, or smell one thing?
For example, if you only wanted to see bees, you are unable to see anything unless a bee comes into frame, in which case you are only able to see a bee.
You could also decide to choose something that you cannot normally sense (e.g. hearing bat echolocation sounds)
Site and taste are something that would be a bummer to live without, smelling has been out of the question for over a decade, so I'm absolutely NOT going back to it, and that leaves sound.
I am unsure I could live without music.
Edit: forgot feel. Not as important to me as music.
It would be the least restrictive but the most oppressive. Anosmia sucks according to a buddy who lost it when he contracted COV SARS 2/COVID 19 five years ago