Now consider that Scripps Research, who is developing this, is US-based and receives a lot of federal government funding, and that Trump/Musk/DOGE have been slashing and burning all kinds of federal science staffing and funding. Also consider that their main federal funding comes from HHS, which RFK Jr., notorious vaccine hater, heads.
Then weep. Progress on this may be stalled for a long time.
Meanwhile, in the U.S. I'm sitting here wondering if we'll even have a flu shot available for next winter, let alone a new vaccine that can protect from Covid and the common cold.
After the most recent flu or cold I had. I would do anything for a cold vaccine. Flu shot likely kept me safe from that last bug I had. But still would like a cold vaccine to.
OK, so if I understand this correctly, they don't train the immune system to target these sugars, since they're used by human cells. Instead, they remove them during the vaccine administration so the immune system can train on the bare spike protein. Cool. Now how would this help when new virus copies come in with sugar-coated proteins, some time after the sugar stripping agent is gone from the system?
Coronaviruses are not the only cause for what is considered the "common cold". I remember that some Rhinoviruses, Adenoviruses and I think a forth family of viruses also cause symptoms that are counted as a cold. It's kind of a catch all term.
I wish they had detailed how the removal of glycans is accomplished. Alas, Wikipedia doesn't even have an article about "glycoengieering", which would likely be the term for this method.
Edit: oh, I also mistunderstood. I started thinking that it accomplishes removal of glycans from the invading virus, but instead it's only removal of glycans from the vaccine, exposing more of the virus, leading to more diverse antibodies. Which is far more doable, and not a big technical novelty. But apparently, quite useful. :)
[Gravely voice] "Look if you want to put that unproven poison in your body I would not recommend doing when alternatives exist, like oranges, and Vitamin D, and death."