Longterm use of Proton Pump Inhibiters linked to dementia
Longterm use of Proton Pump Inhibiters linked to dementia

New link between acid reflux medicines and dementia

Link to study: American Academy of Neurology
After adjusting for factors such as age, sex and race, as well as health-related factors such as high blood pressure and diabetes, researchers found people who had been taking acid reflux drugs for more than 4.4 years had a 33% higher risk of developing dementia than people who never took the drugs.
“A buzzy new study on heartburn meds and dementia doesn’t actually clarify anything”
https://www.vox.com/health/2023/8/10/23827408/dementia-heartburn-proton-pump-inhibitors-ppi-prilosec
“Importantly, the study comes on the heels of several larger, higher-quality studies showing the exact opposite of its conclusions — namely, that these medications do not portend an increased risk of dementia.”
Thank you for that. I take anti heartburn meds due to acid reflux and glad to hear not going get dementia from it.
Sir, this is a Wendy's.
The Vox article does a better job of communicating the findings without the hyperbolic headline. The study wasn’t explicitly designed to look for association. Nonetheless, the data is there.
Neither study does a particularly good job determining causality. The higher quality study was limited in time (3 years) and participant age but perhaps the findings also broadly apply.