It's fucked, but I will warn you it's about as hated as it is loved. If you want to watch it and you don't have the option for a theatre I highly recommend keeping your phone in the other room and closing all your tabs - it kind of demands you give it your full attention to allow it to sink into your psyche.
Ghost World and it's spiritual successor The Last Black Man in San Fransisco. They're not portraits of despair, but they have an underlying melancholy and poignancy that affected and stuck with me me more than most tragedies I've watched.