Adoration of the Mystic Lamb by Hubert van Eyck and Jan van Eyck, 1432
If you ever get the chance to inspect one of van Eyck's altar pieces in real life, then go do it. The level of detail is astonishing. You can basically zoom in on a part of the meadow or the lamb's fell and it's like a painting on its own.
The ghent altar crystal rod is fucking crazy, haven't seen it in person but it's quite literally my favorite painting series.
https://legacy.closertovaneyck.be/#viewer/id1=13&id2=0