I'm currently running Ubuntu, but the way things are going with snap et Al I'm looking to move to something else soon.
My software setup has barely changed in a long time. Ardour is the core of all my production, I use qjackctl for handling Jack, Hydrogen for drums and then occasionally throw in a bit of Renoise or Bitwig for extra synth/sampler needs. I like to keep it simple and this really works for me.
It seems like snap is a bit of a disaster. I have a VM running Ubuntu for testing some things and ended up completely removing snap it was taking up so much space.