What problems can I expect using Linux (Fedora) with an NVIDIA GPU?

I'm planning on getting a laptop within the next month which will be my daily driver for university, and it has a RTX 5060. I know people have lots of issues with NVIDIA on Linux, but I don't know of any specific issues. What issues can I expect running Fedora 42 (KDE) on this device?

I am not responding to most comments here, but I am silently taking them into account.