Maybe recklessly isn't the right word, but there are emergency medications that are administered rectally or nasally where it's better to be quick than gentle. Rectally administered diazepam for seizures is a good example.
A fungal infection most common amongst teenagers forced to wear sweaty unwashed clothes over and over again for gym and sports because the school system is somehow set up too stupidly to effectively deal with mildewy clothing in 2025
It can happen to anyone. It's just super common amongst teens because enforcing and facilitating hygiene for young men is the lowest priority in our society for some reason