I use Firefox everywhere which means I have ads blocking everywhere, including and especially on Android. All my tabs are synced and are easily transferred between devices.
I use it on a Pixel 5 and even there it is fluid while browsing. Only on Youtube there is the slightest stutter for HD Videos. Heavy sites like Discourse fora or Cryptpad or such work flawlessly.
I use both on a Galaxy Fold 5 and can confirm Chromium based browsers are smoother. Although I still use Waterfox on my phone. I just keep a Chromium based browsers in case a website doesn't work when I visited it using Waterfox.
There are other ways to block ads. Adguard does a great job on Android. It establishes a local VPN, so it can do HTTP[S] content filtering in addition to DNS blocking.
Ive been using Firefox on Android for years but it really needs some TLC. It doesn't support scaling to a tablet/desktop UI at all so it doesn't work well in DeX or anything larger than a phone. I also recently had to swap to Brave because I noticed Firefox was draining a lot of battery all of a sudden. There's some kind of leak or running process that isn't sleeping properly. In a few months I'll re-install and try again.