On the other hand: i dont play games to enjoy while thinking about being dirty, having ill fitting clothes, running out of medicine and period products, etc.
Thats all irritating stuff i have to worry about in reality.
I dont want to have to think about those things in game; those arent fun mechanics.
Would make speedrunning weirder than it is. "Alright we are choosing the male here because females are trash and we ain't got time for feminine products."
new vegas, choose to play as a woman so you can seduce the correct person and get an advantage
though precisely because it is postapocalyptic it's less of an advantage than you'd think, because the NCR can't exactly afford to not put women in positions of power if they're competent, and a shotgun does tend to even the field somewhat..