The comments in the thread don't mention Steam itself, but it's that running all the 32 bit games will become a problem. Steam's flatpak packages the 32 bit packages so that can get around this change, but the flatpak is not official and does not support all features. Steam themselves only provide the RPM for Fedora.
I'm no expert, and I'm running Bazzite (and previously Nobara), both of which have the RPM installed by default so I don't think I've ever used the Steam Flatpak. But things mentioned in the thread are VR and Gamescope.
I do wonder if any issues are related to permission restrictions that could be resolved editing permissions with Flatseal, but I don't know enough about the issues.
Ah yeah. Would be unfortunate. Bazzite was the least amount of setup i've ever had to do with linux and is the only repo I could recommend to someone non-technical