Guanfacine was a miracle for me. I couldn’t tolerate stimulants and while the initial fatigue was significant, my focus improved significantly and quickly. Not as suddenly or dramatically as a stimulant (which I was able to take after a couple of years of guanfacine, I was in bad shape at first).
I still take a small dose as an adjunct along with a stimulant.
I don’t think so. I tried atomoxetine first and it also didn’t help so far, at 25, 40, or 80mg. At least the guanfacine is not giving me any noticeable side effects. The atomoxetine caused me to exhibit more hyperactive symptoms (I’m Primary inattentive) for the first two days but then went away; I did feel cold in the afternoons and I also developed some mild erectile dysfunction ( went away when I stopped taking it). I think next stop will be a stimulant, not sure what I’ll start with. I’ll have to stop taking edibles because they’ll need me to take a drug test first before I get a stimulant rx