Beginning with PDF 1.6, the size of the default user space unit may be set with the UserUnit entry of the page dictionary. Acrobat 7.0 supports a maximum UserUnit value of 75,000, which gives a maximum page dimension of 15,000,000 inches (14,400 * 75,000 * 1 ⁄ 72). The minimum UserUnit value is 1.0 (the default).
15 million inches happens to be exactly 381 km Source
Remark: The side length of the square correspods to 381 km, subsequently, its area is 145161 km^2 .
381 km^2 are slightly smaller than the city of Cologne.