If I ever get confronted by a Christian specifically, I have John 6, 37 locked and loaded.
Other than that, I want to try my best and have an actual conversation and explain things. It seems to me that many transphobes just don't know jackshit, and fearing or hating the unknown is all too common.
I guess that'll depend on how I'm feeling on any given day though. I know won't always have the patience for it.
But yeah, as said before, the whole Book of John is a stark contrast to everything a religiously motivated bigot would say. But then again, these people will always find a way to twist the argument in their favour.
Can't explain things to someone who isn't open to it.