For MGSV if you haven't cheated yet I suggest it just for the money at least.
Download a cheat table and run cheat engine.
I don't like the base building parts of games so I just blew through that by giving myself all the money.
That way I can just do the mission parts of the game without caring what is going on at mother base.
i'll keep my save cheat free until i decide if the building is working for me or not. if not i'll consider useing a cheat. when i played last i don't remember getting to mother base. i think i got to the first objective and stopped playing iirc.
I only have a few hours a week to play so I like to make the most of my time by playing the fun parts.
If a game is single player then cheating let's me enjoy the little time I have to play it without grinding.