Sleeping pills stop the brain’s system for cleaning out waste
Sleeping pills stop the brain’s system for cleaning out waste
A specialized system sends pulses of pressure through the fluids in our brain.
Her study found the glymphatic clearance was mediated by a hormone called norepinephrine and happened almost exclusively during the NREM sleep phase. But it only worked when sleep was natural. Anesthesia and sleeping pills shut this process down nearly completely.
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The study was only on zolpidem. IMO it can probably be generalised to other Z drugs, and possibly benzos. Drugs that work by entirely different mechanisms like melatonin and orexin antagonists could be completely different.
What about Benadryl?
Unknown, but it's an anticholinergic, and those are associated with dementia.