I'll always take the time to withhold consent on any cookie banner, no matter how far down I have to scroll or how many levels of dialogs I have to go through.
The ghostery addon does that whole decline process automatically, and also randomizes data that is mandatory to use the site, to help hide who you actually are. I never see these popups anymore, and I have cookies set to clear on browser close, which I do at least once a day to clean up whatever’s left over.