I could see the US breaking up along political lines, but that's going to go a lot worse for most Red states than they think it is. It's still pretty unlikely.
What's likely going to happen is just more bitching and moaning and gerrymandering.
Let it break up. Once the reds separate, it won't be US territory, and we can bomb them out of existence and re-take the land without those traitorous bastages.
We won't have to. Nearly all, if not fully all "red states" receive more in federal funding than they pay in taxes. If they were to secede their econonomies would crash in short order. It would be like Brexit times 10.
And any Democrats in Alabama, which is about a third of the population, I suppose you consider to just be collateral damage whose deaths are just a necessary cost?