Get a keyboard with layers. You'll thank yourself later. So much damn desk space open to anything. A cup of juice. The mouse in between the two halves of the keyboard (if it's a split one like mine), no need for extra buttons that take up so much space just sitting there 99% of the time.
Doesn't really address my point. If your keyboard forces your hand too far off the side... Even if your mouse has a ton of mat space over there, you still have to reach way over there.
I have my mouse in between my two keyboard halves. Off to the side if I'm gaming, and using only one half of the keyboard, the other half unplugged, or just moved up and out of the way.
Yeah I started with a TKL from WASD Keyboards (which seemed like a company that was doing okay, but just suddenly vanished) and it served me great for a year or so and it's still a pretty good keyboard, but I had one look at the ZSA Voyager and I knew I had to have that baby. Only 52 keys, column-staggered, split keyboard. There's so much space on my desk now. I can even unplug one half and get even more space for my mouse if playing FPS games. Programmable layers, LEDs, multi-function keys. It's got the works. Highly recommended piece of hardware IMO.